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DSIP (Delta Sleep-inducing Peptide) is a neuropeptide found in the hypothalamus, pituitary, and adrenal glands. Its isolation has allowed for extensive research which has found several possible primary and peripheral roles of this peptide. First, DSIP has been shown to induce sleep. Second, DSIP can possible be used as an analgesic in treatment of chronic pain, sometimes as an adjunct treatment. Third, DSIP has been shown to block ACTH release and decrease levels of ACTH, stimulate LH release, and act as an inhibitor of the secretion of somatostatin. The source of production of DSIP is yet unknown; it may be produced in the central nervous system or in a peripheral organ. It is thought to pass through the blood-brain barrier (BBB) more easily than most known neuropeptides. As mentioned, DSIP has shown positive results in inducing slow-wave EEG (sleep). It has been shown to help treat narcolepsy and restore disturbed sleep patterns to normal sleep rhythms. [5]
DSIP Amino Acid Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
DSIP, 5mgs
DSIP Amino Acid Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
DSIP, 5mgs
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